
🟦 Key Points :
- Strengthen the skin’s natural barrier and cohesion
- Limit water loss and maintain hydration
- Usable in nutrition and cosmetics
- Improve hydration and barrier function according to studies
What are NP ceramides?
NP ceramides are lipids present in the outer layer of the skin. They connect the cells and reinforce the lipid matrix. This structure reduces water loss and protects against external aggressions. They are very close to the ceramides naturally produced by the skin, which promotes their absorption.
Did you know?
The amount of ceramide in the skin decreases with age, which can increase dryness.
How do NP ceramides work?
Main action
They strengthen the lipid matrix and limit dehydration and also protect the skin from cold, pollution and UV rays.
Tissue-level effects
Although NP ceramides help maintain skin suppleness and comfort, they also support epidermal cohesion, gently regulate skin inflammation, and contribute to the overall integrity and resilience of the skin barrier.

Benefits for skin longevity
A strong skin barrier reflects cellular vitality. NP ceramides support the skin’s natural aging process, helping maintain function and resilience without forcing or stressing its natural mechanisms.
The main benefits
By supporting the skin’s natural ability to retain water, NP ceramides help maintain suppleness and comfort. Their role in reinforcing the lipid barrier may contribute to limiting dryness and improving overall skin hydration, particularly when the skin barrier is weakened or exposed to environmental stressors.
Protection of the skin barrier
By strengthening the integrity of the epidermis, NP ceramides support the skin’s natural barrier function. They help protect it from everyday low-grade external aggressions. This reinforcement contributes to maintaining balance at the surface of the skin over time without disrupting its natural mechanisms.
Natural sources
- Rice bran
- Whole wheat
- Soy
- Corn
- Sweet potato
Dosage, forms and bioavailability
NP ceramides are commonly used as a dietary supplement at doses ranging from 20 to 40 mg per day, as reported in clinical studies. They are also available in cosmetic formulations for topical use. When taken orally, their absorption may be improved when consumed with dietary lipids. Noticeable effects on skin hydration and barrier function are generally observed after several weeks of consistent use.
Security
- Respect daily dose
- Rare and mild side effects such as
- Make sure to have a medical advice if you’re pregnant, breastfeeding or have chronic conditions
How to integrate NP ceramides into a longevity routine
You can integrate NPC into your routine in different ways.
- When: during a meal containing fats
- With what: foods or anything else containing omega-3, vitamin E, or collagen
- For whom: for those who have dry, mature skin or are exposed to environmental aggressions
What if the skin barrier supported skin vitality?
NP Ceramides strengthen the barrier and maintain hydration naturally. They respect the skin’s biological rhythm and support its vitality over the long term. A simple daily routine can thus promote comfortable and resistant skin, while supporting cellular balance.
Sources
- Uchiyama, T., et al. (2018).
Oral intake of glucosylceramide improves skin barrier function.
Journal of Dermatological Science, 90(3), 237–244.
https://pubmed.ncbi.nlm.nih.gov/29661636/
- Matsumoto, M., et al. (2019).
Effect of oral ceramide supplementation on skin hydration and barrier function in healthy adults.
Clinical, Cosmetic and Investigational Dermatology, 12, 477–486.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6616925/
- Imokawa, G., et al. (1991).
Decreased level of ceramides in stratum corneum of atopic dermatitis.
Journal of Investigative Dermatology, 96(4), 523–526.
https://pubmed.ncbi.nlm.nih.gov/2007799/